Well sort of. The same signals and number of wires are used, but with iSATA, the transmission voltage from the host may range from 400 to 600 millivolts. The receiver must be able to decode voltages between 325 and 600mV. With the longer 2 meter eSATA cables, in order to account for additional losses, the minimum voltage transmitted is raised from 400mV to 500mV, and receiver sensitivity is decreased to 240mv. These changes accommodate any additional degradation with the longer cables and additional connectors in the signal path.